Dimethyl sulfoxide, a convenient solvent of 7,12-dimethylbenz(a)anthracene for intravenous injection.

SUMMARY Dimethyl sulfoxide is a convenient solvent of 7,12-dimethylbenz(a)anthracene and related polycycic aromatic hydrocarbons for i.v. injection. As judged by its ability to induce both adrenal necrosis and mammary tumors, this solu tion is at least as active as fatty emulsions of 7,12-dimethyl benz(a)anthracene now in general use. While the preparation of emulsions is timeconsuming andrequires special equip ment, the solution can be made quickly and economically in every laboratory.